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PDE4B/C/D(Phospho Ser133/119/190) Polyclonal Antibody, 100ul Adenovirus Packaging It is expressed at low

SKU: 4541902180

4.1
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PDE4B/C/D(Phospho Ser133/119/190) Polyclonal Antibody, 100ul Adenovirus Packaging It is expressed at lowThis gene is a member of the type IV, cyclic AMP (cAMP) specific, cyclic nucleotide phosphodiesterase (PDE) family. The encoded protein regulates the cellular concentrations of cyclic nucleotides and thereby play a role in signal transduction. Altered activity of this protein has been associated with schizophrenia and bipolar affective disorder. Alternative splicing and the use of alternative promoters results in multiple transcript variants encoding

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Description

It is expressed at low levels in the cytoplasm of pro-B and pre-B cells and present on the cell surface only at mature stages of B-cell differentiation

Selectively inhibits the phosphatase activity of PPP1C

and is located within the NIDDM1 region

Interacts with LCP2 and ZAP70

PDE4B/C/D(Phospho Ser133/119/190) Polyclonal Antibody, 100ul Adenovirus Packaging It is expressed at lowThis gene is a member of the type IV, cyclic AMP (cAMP) specific, cyclic nucleotide phosphodiesterase (PDE) family. The encoded protein regulates the cellular concentrations of cyclic nucleotides and thereby play a role in signal transduction. Altered activity of this protein has been associated with schizophrenia and bipolar affective disorder. Alternative splicing and the use of alternative promoters results in multiple transcript variants encoding

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