PRPF31 Polyclonal Antibody, 100ul Peptide Synthesis Mutations affecting this gene are

Mutations affecting this gene are the cause of autosomal recessive hyper-IgM immunodeficiency type 3 (HIGM3)

The receptor is an integral membrane protein that is readily detectable and localized to two specific regions of the brain

acting as a homodimer to convert naturally-occuring but harmful superoxide radicals to molecular oxygen and hydrogen peroxide

The protein activates STK11 leading to the phosphorylation of both proteins and excluding STK11 from the nucleus

PRPF31 Polyclonal Antibody, 100ul Peptide Synthesis Mutations affecting this gene arePRPF31 encodes a component of the spliceosome complex and is one of several retinitis pigmentosa causing genes. When the gene product is added to the spliceosome complex, activation occurs.