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Rb Monoclonal Antibody, 100ul Liquid Handling &Storage Expressed at lower levels in

SKU: 45244320472

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Rb Monoclonal Antibody, 100ul Liquid Handling &Storage Expressed at lower levels inThe protein encoded by this gene is a negative regulator of the cell cycle and was the first tumor suppressor gene found. The encoded protein also stabilizes constitutive heterochromatin to maintain the overall chromatin structure. The active, hypophosphorylated form of the protein binds transcription factor E2F1. Defects in this gene are a cause of childhood cancer retinoblastoma (RB), bladder cancer, and osteogenic sarcoma.

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Description

Expressed at lower levels in brain

In response to interferon (IFN)

CLCN7 encodes chloride channel 7

Src family tyrosine kinase) encodes a nonreceptor tyrosine-kinase of the src family of proto-oncogenes that are typically involved in cell proliferation and differentiation

Rb Monoclonal Antibody, 100ul Liquid Handling &Storage Expressed at lower levels inThe protein encoded by this gene is a negative regulator of the cell cycle and was the first tumor suppressor gene found. The encoded protein also stabilizes constitutive heterochromatin to maintain the overall chromatin structure. The active, hypophosphorylated form of the protein binds transcription factor E2F1. Defects in this gene are a cause of childhood cancer retinoblastoma (RB), bladder cancer, and osteogenic sarcoma.

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