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Flk-1 Polyclonal Antibody, 20ul[BT-AP03269] Centrifugal Filter Mutations in COL17A1 are associated

SKU: 45046432026

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SEK97.20 SEK139.20

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Flk-1 Polyclonal Antibody, 20ul[BT-AP03269] Centrifugal Filter Mutations in COL17A1 are associatedVEGF R1 is one of the five receptor tyrosine kinases (RTKs) (Flt 1, KDR Flk 1, Flt 4, tie 1, and tek tie 2) whose expression is almost exclusively restricted to the endothelial cells. Tie 1 and tek tie 2 define a new class of RTKs containing two immunoglobulin like domains, three EGF homology domains and three fibronectin type III domains in their extracellular regions. Flt 1, KDR Flk 1 and Flt 4 are members of the class III subfamily of RTKs

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Description

Mutations in COL17A1 are associated with both generalized atrophic benign and junctional epidermolysis bullosa

Studies of the mouse and chick homologs revealed roles in midbrain and limb development

organogenesis

An important paralog of C1R is HP

Flk-1 Polyclonal Antibody, 20ul[BT-AP03269] Centrifugal Filter Mutations in COL17A1 are associatedVEGF R1 is one of the five receptor tyrosine kinases (RTKs) (Flt 1, KDR Flk 1, Flt 4, tie 1, and tek tie 2) whose expression is almost exclusively restricted to the endothelial cells. Tie 1 and tek tie 2 define a new class of RTKs containing two immunoglobulin like domains, three EGF homology domains and three fibronectin type III domains in their extracellular regions. Flt 1, KDR Flk 1 and Flt 4 are members of the class III subfamily of RTKs

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