JIP4 Polyclonal Antibody, 100ul Digital Burette suggesting a role of RB3

suggesting a role of RB3 during neuroblastoma differentiation

|PTM:Phosphorylated when associated with the catalytic subunit

and studies in rat suggest that alternative use of the two translation initiation sites results in N-terminally distinct protein isoforms with different subcellular localization

Members of this subfamily are characterized by an extracellular V-set immunoglobulin-like domain followed by two C2-set immunoglobulin-like domains| and the cytoplasmic tyrosine-based motifs ITIM and SLAM-like

JIP4 Polyclonal Antibody, 100ul Digital Burette suggesting a role of RB3This gene encodes a member of the cancer testis antigen gene family. The encoded protein functions as a scaffold protein that structurally organizes mitogen activated protein kinases and mediates c Jun terminal kinase signaling. This protein also binds to kinesin 1 and may be involved in microtubule based membrane transport. This protein may play a role in tumor growth and development. Alternate splicing results in multiple transcript variants.