PUMA Polyclonal Antibody, 20ul Antisense Oligonucleotides An important paralog of this
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PUMA Polyclonal Antibody, 20ul Antisense Oligonucleotides An important paralog of thisBBC3 encodes a member of the BCL 2 family of proteins. This family member belongs to the BH3 only pro apoptotic subclass. BCL2 binding component 3 cooperates with direct activator proteins to induce mitochondrial outer membrane permeabilization and apoptosis. It can bind to anti apoptotic Bcl 2 family members to induce mitochondrial dysfunction and caspase activation. Because of its pro apoptotic role, BBC3 is a potential drug target for cancer
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