SH2B3 Polyclonal Antibody, 50ul Buffer Solutions one encoding a secreted isoform

one encoding a secreted isoform and the others encoding nonsecreted isoforms

It plays a putative role in tumorigenic reversion and may control cell proliferation

and may be involved in pancreatic lithogenesis

High affinity receptor for urotensin-2 and urotensin-2B

SH2B3 Polyclonal Antibody, 50ul Buffer Solutions one encoding a secreted isoformThis gene encodes a member of the SH2B adaptor family of proteins, which are involved in a range of signaling activities by growth factor and cytokine receptors. The encoded protein is a key negative regulator of cytokine signaling and plays a critical role in hematopoiesis. Mutations in this gene have been associated with susceptibility to celiac disease type 13 and susceptibility to insulin dependent diabetes mellitus. Alternatively spliced