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LATS1(Phospho-Thr1079) Rabbit Polyclonal Antibody, 100ul sgRNA Oligos Diseases associated with REG4 include

SKU: 43603105218

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LATS1(Phospho-Thr1079) Rabbit Polyclonal Antibody, 100ul sgRNA Oligos Diseases associated with REG4 includeThe protein encoded by this gene is a putative serine threonine kinase that localizes to the mitotic apparatus and complexes with cell cycle controller CDC2 kinase in early mitosis. The protein is phosphorylated in a cell cycle dependent manner with late prophase phosphorylation remaining through metaphase. The N terminal region of the protein binds CDC2 to form a complex showing reduced H1 histone kinase activity indicating a role as a negative

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Description

Diseases associated with REG4 include ulcerative colitis

with preferential expression from the maternal allele in placenta and liver

The encoded protein lacks the protein destabilizing (PEST) sequence that is present in other family members

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LATS1(Phospho-Thr1079) Rabbit Polyclonal Antibody, 100ul sgRNA Oligos Diseases associated with REG4 includeThe protein encoded by this gene is a putative serine threonine kinase that localizes to the mitotic apparatus and complexes with cell cycle controller CDC2 kinase in early mitosis. The protein is phosphorylated in a cell cycle dependent manner with late prophase phosphorylation remaining through metaphase. The N terminal region of the protein binds CDC2 to form a complex showing reduced H1 histone kinase activity indicating a role as a negative

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