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MBL-C Polyclonal Antibody, 50ul[BT-AP05258] Measuring Instruments Aberrations in the chromosomal region

SKU: 4323896366

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MBL-C Polyclonal Antibody, 50ul[BT-AP05258] Measuring Instruments Aberrations in the chromosomal regionMBL2 (mannose binding lectin 2) encodes the soluble mannose binding lectin or mannose binding protein found in serum. The protein encoded belongs to the collectin family and is an important element in the innate immune system. The protein recognizes mannose and N acetylglucosamine on many microorganisms, and is capable of activating the classical complement pathway. Deficiencies of MBL2 have been associated with susceptibility to autoimmune and

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Description

Aberrations in the chromosomal region encoding this gene are associated with non-Hodgkin lymphoma and multiple myeloma

the protein moiety binds collagen fibrils and the highly charged hydrophilic glycosaminoglycans regulate interfibrillar spacings

such as by 2-hydroxylation of the N-acyl chain

Use of alternate promoters and alternative splicing result in multiple transcript variants encoding different isoforms

MBL-C Polyclonal Antibody, 50ul[BT-AP05258] Measuring Instruments Aberrations in the chromosomal regionMBL2 (mannose binding lectin 2) encodes the soluble mannose binding lectin or mannose binding protein found in serum. The protein encoded belongs to the collectin family and is an important element in the innate immune system. The protein recognizes mannose and N acetylglucosamine on many microorganisms, and is capable of activating the classical complement pathway. Deficiencies of MBL2 have been associated with susceptibility to autoimmune and

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