SREBP-1 Polyclonal Antibody, 50ul[BT-AP08553] Sample Library Tubes Heterodimers consisting of alpha and

Heterodimers consisting of alpha and gamma subunits have also been described

Allelic variants are associated with prostate and brain cancer susceptibility

The encoded protein contains a C-terminal caspase activation and recruitment domain (CARD)

The neck region is important for homo-oligomerization which allows the receptor to bind multivalent ligands with high avidity

SREBP-1 Polyclonal Antibody, 50ul[BT-AP08553] Sample Library Tubes Heterodimers consisting of alpha andSREBF1 encodes a transcription factor that binds to the sterol regulatory element 1 (SRE1), which is a decamer flanking the low density lipoprotein receptor gene and some genes involved in sterol biosynthesis. Sterol regulatory element binding protein 1 is synthesized as a precursor that is attached to the nuclear membrane and endoplasmic reticulum. Following cleavage, the mature protein translocates to the nucleus and activates transcription by