Vav(Phospho Tyr174) Polyclonal Antibody, 100ul NGS Oligos The encoded protein also plays

The encoded protein also plays a role in the regulation of epidermal growth factor receptor turnover and actin remodelling

Members of this family are guanosine nucleotide exchange factors for Rho GTPases and defined by the presence of conserved DOCK-homology regions

The SFPQ-NONO/SF-1 complex binds to the CYP17 promoter and regulates basal and cAMP-dependent transcriptional avtivity

Mutations in this gene can cause combined oxidative phosphorylation deficiency 14 (Alpers encephalopathy)

Vav(Phospho Tyr174) Polyclonal Antibody, 100ul NGS Oligos The encoded protein also playsThis gene is a member of the VAV gene family. The VAV proteins are guanine nucleotide exchange factors (GEFs) for Rho family GTPases that activate pathways leading to actin cytoskeletal rearrangements and transcriptional alterations. The encoded protein is important in hematopoiesis, playing a role in T cell and B cell development and activation. The encoded protein has been identified as the specific binding partner of Nef proteins from HIV 1.