Stat5 Polyclonal Antibody, 50ul[BT-AP08636] Metabolic enzymes tool compounds The gene has previously been

The gene has previously been referred to as synaptotagmin XI but has been renamed synaptotagmin XII to be standard with mouse and rat official nomenclature

it is one of the major cellular poly(rC)-binding proteins

forming an intermediate deoxyhypusine residue

This gene encodes a member of the annexin family

Stat5 Polyclonal Antibody, 50ul[BT-AP08636] Metabolic enzymes tool compounds The gene has previously beenStat5 is activated in response to a wide variety of ligands including IL 2, GM CSF, growth hormone and prolactin. Phosphorylation at Tyr694 is obligatory for Stat5 activation. This phosphorylation is mediated by Src upon erythropoietin stimulation. Stat5 is constitutively active in some leukemic cell types. Phosphorylated Stat5 is found in some endothelial cells treated with IL 3, which suggests its involvement in angiogenesis and cell motility.