HEPS Polyclonal Antibody, 50ul Proteases CA4 encodes a glycosylphosphatidyl-inositol-anchored membrane

CA4 encodes a glycosylphosphatidyl-inositol-anchored membrane isozyme expressed on the luminal surfaces of pulmonary (and certain other) capillaries and proximal renal tubules

Efficiently abrogates E2F1-dependent CDKN2A transactivation/de-repression

GO annotations related to this gene include hydrolase activity

A sequence polymorphism has been identified in the 3'UTR of the third exon

HEPS Polyclonal Antibody, 50ul Proteases CA4 encodes a glycosylphosphatidyl-inositol-anchored membraneThis gene encodes a type II transmembrane serine protease that may be involved in diverse cellular functions, including blood coagulation and the maintenance of cell morphology. Expression of the encoded protein is associated with the growth and progression of cancers, particularly prostate cancer. The protein is cleaved into a catalytic serine protease chain and a non catalytic scavenger receptor cysteine rich chain, which associate via a single