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Raf-1 Polyclonal Antibody, 100ul[BT-AP07621] Multiplex Immunoassays It requires divalent metal ions

SKU: 41321345829

4.7
USD123.75 USD162.75

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Raf-1 Polyclonal Antibody, 100ul[BT-AP07621] Multiplex Immunoassays It requires divalent metal ionsRAF1 (Raf 1 proto oncogene, serine threonine kinase) is the cellular homolog of viral raf gene (v raf). The encoded protein is a MAP kinase kinase kinase (MAP3K), which functions downstream of the Ras family of membrane associated GTPases to which it binds directly. Once activated, the cellular RAF1 protein can phosphorylate to activate the dual specificity protein kinases MEK1 and MEK2, which in turn phosphorylate to activate the serine threonine

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Description

It requires divalent metal ions and an intact Nudix motif for enzymatic activity

The gene mutation results in primary NAA deficiency (hypoacetylaspartia)

It binds secretin which is the most potent regulator of pancreatic bicarbonate

Y genotype

Raf-1 Polyclonal Antibody, 100ul[BT-AP07621] Multiplex Immunoassays It requires divalent metal ionsRAF1 (Raf 1 proto oncogene, serine threonine kinase) is the cellular homolog of viral raf gene (v raf). The encoded protein is a MAP kinase kinase kinase (MAP3K), which functions downstream of the Ras family of membrane associated GTPases to which it binds directly. Once activated, the cellular RAF1 protein can phosphorylate to activate the dual specificity protein kinases MEK1 and MEK2, which in turn phosphorylate to activate the serine threonine

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