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Phospho-Bcl-2 (S70) Polyclonal Antibody, 100ul[BT-PHS00492] Site-directed Mutagenesis WD repeats are minimally conserved

SKU: 41191799749

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Phospho-Bcl-2 (S70) Polyclonal Antibody, 100ul[BT-PHS00492] Site-directed Mutagenesis WD repeats are minimally conservedBCL2 encodes an integral outer mitochondrial membrane protein that blocks the apoptotic death of some cells such as lymphocytes. Constitutive expression of BCL2, such as in the case of translocation of BCL2 to Ig heavy chain locus, is thought to be the cause of follicular lymphoma. Alternative splicing results in multiple transcript variants.

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Description

WD repeats are minimally conserved regions of approximately 40 amino acids typically bracketed by gly-his and trp-asp (GH-WD)| which may facilitate formation of heterotrimeric or multiprotein complexes

involved in calcium binding and microtubule stabilization

cAMP and cGMP function as key regulators of many important physiological processes

ERBB3 encodes a member of the epidermal growth factor receptor (EGFR) family of receptor tyrosine kinases

Phospho-Bcl-2 (S70) Polyclonal Antibody, 100ul[BT-PHS00492] Site-directed Mutagenesis WD repeats are minimally conservedBCL2 encodes an integral outer mitochondrial membrane protein that blocks the apoptotic death of some cells such as lymphocytes. Constitutive expression of BCL2, such as in the case of translocation of BCL2 to Ig heavy chain locus, is thought to be the cause of follicular lymphoma. Alternative splicing results in multiple transcript variants.

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