Fes Polyclonal Antibody, 50ul Cell Transfection miscellaneous:The gene maps to 3q26

miscellaneous:The gene maps to 3q26

This gene encodes a nuclear zinc finger protein that functions as a transcriptional repressor

nuclear receptors and basal transcription factors to facilitate nuclear receptors-mediated transcription

Although this gene was isolated as a transforming gene from a melanoma cell line

Fes Polyclonal Antibody, 50ul Cell Transfection miscellaneous:The gene maps to 3q26FES encodes the human cellular counterpart of a feline sarcoma retrovirus protein with transforming capabilities. The gene product has tyrosine specific protein kinase activity and that activity is required for maintenance of cellular transformation. Its chromosomal location has linked it to a specific translocation event identified in patients with acute promyelocytic leukemia but it is also involved in normal hematopoiesis as well as growth factor