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AES Polyclonal Antibody, 50ul Buffer Solutions Alternative splicing results in multiple

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AES Polyclonal Antibody, 50ul Buffer Solutions Alternative splicing results in multipleThe protein encoded by this gene is similar in sequence to the amino terminus of Drosophila enhancer of split groucho a protein involved in neurogenesis during embryonic development. The encoded protein which belongs to the groucho TLE family of proteins can function as a homooligomer or as a heteroologimer with other family members to dominantly repress the expression of other family member genes. Three transcript variants encoding different isoforms

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Description

Alternative splicing results in multiple transcript variants that differ in their subcellular localization and biological activity

including heparan sulfate

Expression of this gene has been shown to be downregulated in tumor progression of human cancers and can be activated by p53 through a consensus binding sequence in the promoter

LOST1 or IFITMD3 (interferon-induced transmembrane domain-containing protein D3)

AES Polyclonal Antibody, 50ul Buffer Solutions Alternative splicing results in multipleThe protein encoded by this gene is similar in sequence to the amino terminus of Drosophila enhancer of split groucho a protein involved in neurogenesis during embryonic development. The encoded protein which belongs to the groucho TLE family of proteins can function as a homooligomer or as a heteroologimer with other family members to dominantly repress the expression of other family member genes. Three transcript variants encoding different isoforms

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