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Stathmin-3 Polyclonal Antibody, 100ul Apoptosis & Autophagy Voltage-gated Ca(2+) and Na+ channels

SKU: 40611171012

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Stathmin-3 Polyclonal Antibody, 100ul Apoptosis & Autophagy Voltage-gated Ca(2+) and Na+ channelsSTMN3 encodes Stathmin 3 which is a member of the stathmin protein family. Members of this protein family form a complex with tubulins at a ratio of 2 tubulins for each stathmin protein. Microtubules require the ordered assembly of alpha and beta tubulins, and formation of a complex with stathmin disrupts microtubule formation and function. A pseudogene of this gene is located on chromosome 22. Alternative splicing results in multiple transcript

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Description

Voltage-gated Ca(2+) and Na+ channels have 4 homologous domains| each containing 6 transmembrane segments| S1 to S6

subcellular location:Translocates to the cytoplasm on phosphorylation where it binds binding to YWHAZ

Among its related pathways are Metabolism and Immune System

Mutations in this gene result in sporadic and familial Paget disease of bone

Stathmin-3 Polyclonal Antibody, 100ul Apoptosis & Autophagy Voltage-gated Ca(2+) and Na+ channelsSTMN3 encodes Stathmin 3 which is a member of the stathmin protein family. Members of this protein family form a complex with tubulins at a ratio of 2 tubulins for each stathmin protein. Microtubules require the ordered assembly of alpha and beta tubulins, and formation of a complex with stathmin disrupts microtubule formation and function. A pseudogene of this gene is located on chromosome 22. Alternative splicing results in multiple transcript

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