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NuMA Polyclonal Antibody, 50ul High Speed Micro-Centrifuges depending on stage of neuronal

SKU: 40587178985

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NuMA Polyclonal Antibody, 50ul High Speed Micro-Centrifuges depending on stage of neuronalNUMA1 encodes a large protein that forms a structural component of the nuclear matrix. The encoded protein interacts with microtubules and plays a role in the formation and organization of the mitotic spindle during cell division. Chromosomal translocation of NUMA1 with the RARA (retinoic acid receptor, alpha) gene on chromosome 17 have been detected in patients with acute promyelocytic leukemia. Alternative splicing results in multiple transcript

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Description

depending on stage of neuronal maturation and neuron type

and like them may bind the catalytic subunit of DNA-dependent protein kinases

Mutations in the gene are associated with localized autosomal recessive hypotrichosis and monilethrix

The small guanosine triphosphatase Rho is implicated in myosin light chain (MLC) phosphorylation| which results in contraction of smooth muscle and interaction of actin and myosin in nonmuscle cells

NuMA Polyclonal Antibody, 50ul High Speed Micro-Centrifuges depending on stage of neuronalNUMA1 encodes a large protein that forms a structural component of the nuclear matrix. The encoded protein interacts with microtubules and plays a role in the formation and organization of the mitotic spindle during cell division. Chromosomal translocation of NUMA1 with the RARA (retinoic acid receptor, alpha) gene on chromosome 17 have been detected in patients with acute promyelocytic leukemia. Alternative splicing results in multiple transcript

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