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Granzyme B Polyclonal Antibody, 100ul Live Cell Imaging During osteoblast maturation the protein

SKU: 40160274087

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Granzyme B Polyclonal Antibody, 100ul Live Cell Imaging During osteoblast maturation the proteinThis gene encodes a member of the granzyme subfamily of proteins, part of the peptidase S1 family of serine proteases. The encoded preproprotein is secreted by natural killer (NK) cells and cytotoxic T lymphocytes (CTLs) and proteolytically processed to generate the active protease, which induces target cell apoptosis. This protein also processes cytokines and degrades extracellular matrix proteins, and these roles are implicated in chronic

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Description

During osteoblast maturation the protein becomes phosphorylated and is exported to the extracellular matrix

which bind to one another in a homophilic manner

The encoded protein specifically binds to the Rho family GTPase Cdc42Hs and can stimulate the GDP-GTP exchange of the isoprenylated form of Cdc42Hs

The encoded protein activates nuclear factor kappa-B and mitogen-activated protein kinase 8 (also called c-Jun N-terminal kinase 1)

Granzyme B Polyclonal Antibody, 100ul Live Cell Imaging During osteoblast maturation the proteinThis gene encodes a member of the granzyme subfamily of proteins, part of the peptidase S1 family of serine proteases. The encoded preproprotein is secreted by natural killer (NK) cells and cytotoxic T lymphocytes (CTLs) and proteolytically processed to generate the active protease, which induces target cell apoptosis. This protein also processes cytokines and degrades extracellular matrix proteins, and these roles are implicated in chronic

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