TOP2A(Phospho Ser1213) Rabbit Polyclonal Antibody, 100ul Serological Pipets The basic leucine zipper ATF-like

The basic leucine zipper ATF-like transcription factor encoded by BATF is a nuclear basic leucine zipper protein that belongs to the AP-1/ATF superfamily of transcription factors

A germline mutation of VHL is the basis of familial inheritance of VHL syndrome

The encoded protein may inhibit c-Jun N-terminal kinase (JNK) independently of CDC42 binding

VitroGel ORGANOID-2

TOP2A(Phospho Ser1213) Rabbit Polyclonal Antibody, 100ul Serological Pipets The basic leucine zipper ATF-likeCatalytic activity: ATP dependent breakage passage and rejoining of double stranded DNA. enzyme regulation: Specifically inhibited by the intercalating agent amsacrine. Control of topological states of DNA by transient breakage and subsequent rejoining of DNA strands. Topoisomerase II makes double strand breaks. miscellaneous: Eukaryotic topoisomerase I and II can relax both negative and positive supercoils whereas prokaryotic enzymes relax only