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AIRE-1 Polyclonal Antibody, 100ul[BT-AP00312] Molecular Sciences while a related enzyme encoded
PLN123.75
PLN147.75
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AIRE-1 Polyclonal Antibody, 100ul[BT-AP00312] Molecular Sciences while a related enzyme encodedAIRE encodes a transcriptional regulator that forms nuclear bodies and interacts with the transcriptional coactivator CREB binding protein. The encoded protein (autoimmune regulator) plays an important role in immunity by regulating the expression of autoantigens and negative selection of autoreactive T cells in the thymus. Mutations in this gene cause the rare autosomal recessive systemic autoimmune disease termed autoimmune polyendocrinopathy with
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