SC65 Polyclonal Antibody, 100ul Recombinant Ab Production Several alternatively spliced transcript variants

Several alternatively spliced transcript variants have been observed

Pseudogenes are present on chromosomes 5 and 22

a constitutively expressed transcript and a cell cycle-regulated transcript

The protein encoded by this gene is a member of the large DEAD-box protein family

SC65 Polyclonal Antibody, 100ul Recombinant Ab Production Several alternatively spliced transcript variantsThis nucleolar protein was first characterized because it was an autoantigen in cases on interstitial cystitis. The protein, with a predicted molecular weight of 50 kDa, appears to be localized in the particulate compartment of the interphase nucleolus, with a distribution distinct from that of nucleolar protein B23. During mitosis it is associated with chromosomes.