Rabbit Caspase 3, CASP3 ELISA Kit, 96T sgRNA Oligos This gene is the founding

This gene is the founding member of the NEDD4 family of HECT ubiquitin ligases that function in the ubiquitin proteasome system of protein degradation

The non-functional allele of ACTN3 is associated with elite athlete status

causing secretion of tumor necrosis factor-alpha (TNF-alpha) and other inflammatory mediators

Mice lacking the homolog gene displayed a male-to-female sex reversal phenotype

Rabbit Caspase 3, CASP3 ELISA Kit, 96T sgRNA Oligos This gene is the foundingInvolved in the activation cascade of caspases responsible for apoptosis execution. At the onset of apoptosis it proteolytically cleaves poly(ADP ribose) polymerase (PARP) at a '216 Asp Gly 217' bond. Cleaves and activates sterol regulatory element binding proteins (SREBPs) between the basic helix loop helix leucine zipper domain and the membrane attachment domain. Cleaves and activates caspase 6, 7 and 9. Involved in the cleavage of huntingtin.