MER/TYRO3(Phospho-Tyr753/Tyr685) Polyclonal Antibody, 100ul Diagnostic Probes & Oligos The voltage dependent anion channel

The voltage dependent anion channel 1 facilitates the exchange of metabolites and ions across the outer mitochondrial membrane and may regulate mitochondrial functions

Interacts with SV40 major capsid protein VP1

Pendred syndrome

The protein functions as a guanine nucleotide exchange factor for the small GTPase RAB5

MER/TYRO3(Phospho-Tyr753/Tyr685) Polyclonal Antibody, 100ul Diagnostic Probes & Oligos The voltage dependent anion channelThis gene is a member of the MER AXL TYRO3 receptor kinase family and encodes a transmembrane protein with two fibronectin type III domains, two Ig like C2 type (immunoglobulin like) domains, and one tyrosine kinase domain. Mutations in this gene have been associated with disruption of the retinal pigment epithelium (RPE) phagocytosis pathway and onset of autosomal recessive retinitis pigmentosa (RP).