RYK Polyclonal Antibody, 100ul Cell Transfection a large E3 ubiquitin ligase

a large E3 ubiquitin ligase that controls cell cycle progression by targeting a number of cell cycle regulators such as B-type cyclins for 26S proteasome-mediated degradation through ubiquitination

PGA5 is found in a cluster of related genes on chromosome 11

double strand DNA break repair and apoptosis

High level expression of CCND2 was observed in ovarian and testicular tumors

RYK Polyclonal Antibody, 100ul Cell Transfection a large E3 ubiquitin ligaseThe protein encoded by this gene is an atypical member of the family of growth factor receptor protein tyrosine kinases, differing from other members at a number of conserved residues in the activation and nucleotide binding domains. This gene product belongs to a subfamily whose members do not appear to be regulated by phosphorylation in the activation segment. It has been suggested that mediation of biological activity by recruitment of a signaling