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NuMA Polyclonal Antibody, 20ul Antibody Humanization JAK1 encodes a membrane protein

SKU: 39760943889

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NuMA Polyclonal Antibody, 20ul Antibody Humanization JAK1 encodes a membrane proteinNUMA1 encodes a large protein that forms a structural component of the nuclear matrix. The encoded protein interacts with microtubules and plays a role in the formation and organization of the mitotic spindle during cell division. Chromosomal translocation of NUMA1 with the RARA (retinoic acid receptor, alpha) gene on chromosome 17 have been detected in patients with acute promyelocytic leukemia. Alternative splicing results in multiple transcript

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Description

JAK1 encodes a membrane protein that is a member of a class of protein-tyrosine kinases (PTK) characterized by the presence of a second phosphotransferase-related domain immediately N-terminal to the PTK domain

The encoded enzyme participates in the DNA repair pathway by initiating base excision repair by removing damaged bases

and deletion variants Ena

X-linked 3) encodes a member of the ALEX family of proteins which may play a role in tumor suppression

NuMA Polyclonal Antibody, 20ul Antibody Humanization JAK1 encodes a membrane proteinNUMA1 encodes a large protein that forms a structural component of the nuclear matrix. The encoded protein interacts with microtubules and plays a role in the formation and organization of the mitotic spindle during cell division. Chromosomal translocation of NUMA1 with the RARA (retinoic acid receptor, alpha) gene on chromosome 17 have been detected in patients with acute promyelocytic leukemia. Alternative splicing results in multiple transcript

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