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EGFR(Phospho Ser695) Polyclonal Antibody, 50ul Micro Centrifuge Tubes Variations in this gene may

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EGFR(Phospho Ser695) Polyclonal Antibody, 50ul Micro Centrifuge Tubes Variations in this gene mayThe protein encoded by this gene is a transmembrane glycoprotein that is a member of the protein kinase superfamily. This protein is a receptor for members of the epidermal growth factor family. EGFR is a cell surface protein that binds to epidermal growth factor. Binding of the protein to a ligand induces receptor dimerization and tyrosine autophosphorylation and leads to cell proliferation. Mutations in this gene are associated with lung cancer.

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Description

Variations in this gene may be associated with susceptibility to systemic lupus erythematosus (SLE)

also known as the V2 receptor

thereby terminating the signal

The encoded protein contains a highly conserved J domain of about 70 amino acids with a characteristic His-Pro-Asp (HPD) motif and may regulate the activity of binding immunoglobulin protein by stimulating ATPase activity

EGFR(Phospho Ser695) Polyclonal Antibody, 50ul Micro Centrifuge Tubes Variations in this gene mayThe protein encoded by this gene is a transmembrane glycoprotein that is a member of the protein kinase superfamily. This protein is a receptor for members of the epidermal growth factor family. EGFR is a cell surface protein that binds to epidermal growth factor. Binding of the protein to a ligand induces receptor dimerization and tyrosine autophosphorylation and leads to cell proliferation. Mutations in this gene are associated with lung cancer.

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