SIRT1 Monoclonal Antibody, 50ul Petri Dishes HNRNPA1 encodes a member of

HNRNPA1 encodes a member of a family of ubiquitously expressed heterogeneous nuclear ribonucleoproteins (hnRNPs)

The gene is a member of both the immunoglobulin superfamily and the leukocyte-associated inhibitory receptor family

The genes encoding the type II cytokeratins are clustered in a region of chromosome 12q12-q13

Alternative splicing generates multiple transcript variants

SIRT1 Monoclonal Antibody, 50ul Petri Dishes HNRNPA1 encodes a member ofThis gene encodes a member of the sirtuin family of proteins, homologs to the yeast Sir2 protein. Members of the sirtuin family are characterized by a sirtuin core domain and grouped into four classes. The functions of human sirtuins have not yet been determined however, yeast sirtuin proteins are known to regulate epigenetic gene silencing and suppress recombination of rDNA. Studies suggest that the human sirtuins may function as intracellular