DNA Ligase IV Polyclonal Antibody, 100ul[BT-AP02653] 3D Culture Mutations in this gene are

Mutations in this gene are associated with Noonan syndrome 5 and LEOPARD syndrome 2

This gene is a member of a photoreceptor-specific gene family and encodes an integral membrane protein found in the photoreceptor disk rim of the eye

CREM encodes a bZIP transcription factor that binds to the cAMP responsive element found in many viral and cellular promoters

Bim/Bod is a pro-apoptotic protein belonging to the BH3-only group of Bcl-2 family members including Bad

DNA Ligase IV Polyclonal Antibody, 100ul[BT-AP02653] 3D Culture Mutations in this gene areThe protein encoded by LIG4 is a DNA ligase that joins single strand breaks in a double stranded polydeoxynucleotide in an ATP dependent reaction. This protein is essential for V(D)J recombination and DNA double strand break (DSB) repair through nonhomologous end joining (NHEJ). This protein forms a complex with the X ray repair cross complementing protein 4 (XRCC4), and further interacts with the DNA dependent protein kinase (DNA PK). Both XRCC4 and