DU4L7 Rabbit Polyclonal Antibody, 100ul Cell Senescence MEKK4 is a major mediator

MEKK4 is a major mediator of environmental stresses that activate the CSBP2 MAPK pathway

Growth arrest-specific 1 plays a role in growth suppression

Terminates the action of GABA by its high affinity sodium-dependent reuptake into presynaptic terminals

which are characterized by multiple defects in peroxisome function

DU4L7 Rabbit Polyclonal Antibody, 100ul Cell Senescence MEKK4 is a major mediatorThis gene is located within a D4Z4 repeat array in the subtelomeric region of chromosome 4q. The D4Z4 repeat is polymorphic in length and a similar D4Z4 repeat array has been identified on chromosome 10. Each D4Z4 repeat unit has an open reading frame (named DUX4) that encodes two homeoboxes; the repeat array and ORF is conserved in other mammals. There is no evidence for transcription of the gene at this locus though RT PCR and in vitro expression