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SESN3 Rabbit Polyclonal Antibody, 50ul Cryopreservation Calcineurin like EF-hand protein 2

SKU: 3881437577

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PLN185.00 PLN206.00

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SESN3 Rabbit Polyclonal Antibody, 50ul Cryopreservation Calcineurin like EF-hand protein 2This gene encodes a member of the sestrin family of stress induced proteins. The encoded protein reduces the levels of intracellular reactive oxygen species induced by activated Ras downstream of RAC alpha serine threonine protein kinase (Akt) and FoxO transcription factor. The protein is required for normal regulation of blood glucose insulin resistance and plays a role in lipid storage in obesity. Alternative splicing results in multiple transcript

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Description

Calcineurin like EF-hand protein 2 shares sequence similarity with calcineurin B and can bind to and stimulate the protein phosphatase activity of calcineurin A (CnA) and functions in the calcineurin/NFAT (nuclear factor of activated T cells) signaling pathway

This nuclear gene encodes a mitochondrial tRNA-modifying enzyme

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which also leads to tumor formation

SESN3 Rabbit Polyclonal Antibody, 50ul Cryopreservation Calcineurin like EF-hand protein 2This gene encodes a member of the sestrin family of stress induced proteins. The encoded protein reduces the levels of intracellular reactive oxygen species induced by activated Ras downstream of RAC alpha serine threonine protein kinase (Akt) and FoxO transcription factor. The protein is required for normal regulation of blood glucose insulin resistance and plays a role in lipid storage in obesity. Alternative splicing results in multiple transcript

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