Dok-2 Polyclonal Antibody, 50ul[BT-AP02698] Hybridoma Antibody Sequencing The regulatory subunit is encoded

The regulatory subunit is encoded by a diverse set of genes that have been grouped into the B/PR55

Eight alternatively spliced transcript variants have been described

The protein may also be involved in the pathophysiology of depression

subcellular location:Expressed diffusely throughout the nucleus

Dok-2 Polyclonal Antibody, 50ul[BT-AP02698] Hybridoma Antibody Sequencing The regulatory subunit is encodedThe protein encoded by DOK2 (docking protein 2)is constitutively tyrosine phosphorylated in hematopoietic progenitors isolated from chronic myelogenous leukemia (CML) patients in the chronic phase. It may be a critical substrate for p210 (bcr abl), a chimeric protein whose presence is associated with CML. This encoded protein binds p120 (RasGAP) from CML cells.