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Rat Bone Morphogenetic Protein 2, BMP-2 ELISA Kit , 96T Cellular Cultivation & Health Management Maintains myogenic progenitors pool by

SKU: 38461869417

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Rat Bone Morphogenetic Protein 2, BMP-2 ELISA Kit , 96T Cellular Cultivation & Health Management Maintains myogenic progenitors pool byInduces cartilage and bone formation. Stimulates the differentiation of myoblasts into osteoblasts via the EIF2AK3 EIF2A ATF4 pathway. BMP2 activation of EIF2AK3 stimulates phosphorylation of EIF2A which leads to increased expression of ATF4 which plays a central role in osteoblast differentiation. In addition stimulates TMEM119, which upregulates the expression of ATF4.

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Description

Maintains myogenic progenitors pool by suppressing differentiation through down-regulation of MYOD1 and is required for satellite cell homing and PAX7 expression (PubMed: 22940113)

Each component of the AHP is kinetically distinct and is mediated by different calcium-activated potassium channels

recognizing and hydrolyzing the peptide bond at the C-terminal glycine of ubiquitin

Secretory calcium-dependent phospholipase A2 that primarily targets extracellular phospholipids with implications in host antimicrobial defense

Rat Bone Morphogenetic Protein 2, BMP-2 ELISA Kit , 96T Cellular Cultivation & Health Management Maintains myogenic progenitors pool byInduces cartilage and bone formation. Stimulates the differentiation of myoblasts into osteoblasts via the EIF2AK3 EIF2A ATF4 pathway. BMP2 activation of EIF2AK3 stimulates phosphorylation of EIF2A which leads to increased expression of ATF4 which plays a central role in osteoblast differentiation. In addition stimulates TMEM119, which upregulates the expression of ATF4.

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