Btk(Phospho-Ser180) Rabbit Polyclonal Antibody, 50ul Erlenmeyer Flasks Pseudogenes corresponding to this gene

Pseudogenes corresponding to this gene are found on chromosomes 4p and 21q

are induced by interferon and hydrolyze GTP to both GDP and GMP (Vestal

and a ubiquitin protein ligase (E3)

PAK4 interacts specifically with the GTP-bound form of Cdc42Hs and weakly activates the JNK family of MAP kinases

Btk(Phospho-Ser180) Rabbit Polyclonal Antibody, 50ul Erlenmeyer Flasks Pseudogenes corresponding to this geneThe protein encoded by this gene plays a crucial role in B cell development. Mutations in this gene cause X linked agammaglobulinemia type 1 which is an immunodeficiency characterized by the failure to produce mature B lymphocytes and associated with a failure of Ig heavy chain rearrangement. Alternative splicing results in multiple transcript variants encoding different isoforms.