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XRCC4 Polyclonal Antibody, 100ul Metabolic enzymes PER2 is upregulated by CLOCK/ARNTL

SKU: 38214560332

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XRCC4 Polyclonal Antibody, 100ul Metabolic enzymes PER2 is upregulated by CLOCK/ARNTLDNA repair protein XRCC4 encoded by XRCC4 functions together with DNA ligase IV and the DNA dependent protein kinase in the repair of DNA double strand breaks. This protein plays a role in both non homologous end joining and the completion of V(D)J recombination. Mutations in this gene can cause short stature, microcephaly, and endocrine dysfunction (SSMED). Alternative splicing generates several transcript variants.

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Description

PER2 is upregulated by CLOCK/ARNTL heterodimers but then represses this upregulation in a feedback loop using PER/CRY heterodimers to interact with CLOCK/ARNTL

Rotor material: stainless steel bodyand adapter

influence the spatial distribution of microtubules within cells and utilize microtubule polarity to translocate cellular components

a unique amino acid formed by the posttranslational modification of only one protein

XRCC4 Polyclonal Antibody, 100ul Metabolic enzymes PER2 is upregulated by CLOCK/ARNTLDNA repair protein XRCC4 encoded by XRCC4 functions together with DNA ligase IV and the DNA dependent protein kinase in the repair of DNA double strand breaks. This protein plays a role in both non homologous end joining and the completion of V(D)J recombination. Mutations in this gene can cause short stature, microcephaly, and endocrine dysfunction (SSMED). Alternative splicing generates several transcript variants.

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