Fes Polyclonal Antibody, 100ul Cell Biology Expression of this gene has

Expression of this gene has been correlated with the grade of the malignancy and proliferative activity in gliomas and melanomas

resulting from unregulated expression of the growth factor

it has only a single zinc finger module

Members of this protein family contain seven putative transmembrane domains and may mediate signaling processes to the interior of the cell via activation of heterotrimeric G proteins

Fes Polyclonal Antibody, 100ul Cell Biology Expression of this gene hasFES encodes the human cellular counterpart of a feline sarcoma retrovirus protein with transforming capabilities. The gene product has tyrosine specific protein kinase activity and that activity is required for maintenance of cellular transformation. Its chromosomal location has linked it to a specific translocation event identified in patients with acute promyelocytic leukemia but it is also involved in normal hematopoiesis as well as growth factor