ERCC1 Monoclonal Antibody(1B10), 20ul Liquid Storage Consumables Two isoforms of ZNF682 exist

Two isoforms of ZNF682 exist as a result of alternative splicing events

conserved DNA elements (heat shock elements or HSEs) and CCAAT boxes

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ZNF682 contains eleven C2H2-type zinc fingers and one KRAB domain through which it is thought to be involved in DNA-binding and transcriptional regulation

ERCC1 Monoclonal Antibody(1B10), 20ul Liquid Storage Consumables Two isoforms of ZNF682 existThe product of this gene functions in the nucleotide excision repair pathway, and is required for the repair of DNA lesions such as those induced by UV light or formed by electrophilic compounds including cisplatin. The encoded protein forms a heterodimer with the XPF endonuclease (also known as ERCC4), and the heterodimeric endonuclease catalyzes the 5' incision in the process of excising the DNA lesion. The heterodimeric endonuclease is also