MEK Kinase-1 Polyclonal Antibody, 100ul[BT-AP05333] Isothermal Amplification Mutations in this gene result

Mutations in this gene result in autosomal recessive spastic ataxia of Charlevoix-Saguenay (ARSACS)

Mutations in this gene cause rhabdoid tumor predisposition syndrome type 2

This gene encodes a cytoplasmic ribosomal protein that is a component of the 60S subunit

Also found in the spleen and testis

MEK Kinase-1 Polyclonal Antibody, 100ul[BT-AP05333] Isothermal Amplification Mutations in this gene resultThe protein encoded by MAP3K1 (mitogen activated protein kinase kinase kinase 1) is a serine threonine kinase and is part of some signal transduction cascades, including the ERK and JNK kinase pathways as well as the NF kappa B pathway. The encoded protein is activated by autophosphorylation and requires magnesium as a cofactor in phosphorylating other proteins. This protein has E3 ligase activity conferred by a plant homeodomain (PHD) in its N