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PARP-1 (Acetyl-K521) Polyclonal Antibody, 50ul Cell Culture & Maintenance Diphthamide is a post-translationally modified

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PARP-1 (Acetyl-K521) Polyclonal Antibody, 50ul Cell Culture & Maintenance Diphthamide is a post-translationally modifiedThis gene encodes a chromatin associated enzyme, poly(ADP ribosyl)transferase, which modifies various nuclear proteins by poly(ADP ribosyl)ation. The modification is dependent on DNA and is involved in the regulation of various important cellular processes such as differentiation, proliferation, and tumor transformation and also in the regulation of the molecular events involved in the recovery of cell from DNA damage. In addition, this enzyme may be

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Description

Diphthamide is a post-translationally modified histidine residue present in elongation factor 2| and is the target of diphtheria toxin

The protein contains the ZAS domain comprised of two widely separated regions of zinc finger motifs| a stretch of highly acidic amino acids and a serine/threonine-rich sequence

ATP6V1D (ATPase H+ transporting V1 subunit D) encodes a component of vacuolar ATPase (V-ATPase)

This gene is expressed predominantly in T-cells

PARP-1 (Acetyl-K521) Polyclonal Antibody, 50ul Cell Culture & Maintenance Diphthamide is a post-translationally modifiedThis gene encodes a chromatin associated enzyme, poly(ADP ribosyl)transferase, which modifies various nuclear proteins by poly(ADP ribosyl)ation. The modification is dependent on DNA and is involved in the regulation of various important cellular processes such as differentiation, proliferation, and tumor transformation and also in the regulation of the molecular events involved in the recovery of cell from DNA damage. In addition, this enzyme may be

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