Rat Desmin, DES ELISA Kit, 96T Funnels KRT18 encodes the type I

KRT18 encodes the type I intermediate filament chain keratin 18

[Isoform 2]: Receptor for the C-X-C chemokine CXCL4 and also mediates the inhibitory activities of CXCL9

Three alternatively spliced transcript variants encoding different isoforms have been found for this gene

It interacts with calcium-modulator and cyclophilin ligand (CAML)

Rat Desmin, DES ELISA Kit, 96T Funnels KRT18 encodes the type IMuscle specific type III intermediate filament essential for proper muscular structure and function. Plays a crucial role in maintaining the structure of sarcomeres, inter connecting the Z disks and forming the myofibrils, linking them not only to the sarcolemmal cytoskeleton, but also to the nucleus and mitochondria, thus providing strength for the muscle fiber during activity. In adult striated muscle they form a fibrous network connecting