EphB1/2(Phospho Tyr594/604) Polyclonal Antibody, 20ul Antibody Humanization Disease-associated mutations tend to be

Disease-associated mutations tend to be clustered in a small region designated the mutation cluster region (MCR) and result in a truncated protein product

This gene encodes a member of the FAM69 family of cysteine-rich type II transmembrane proteins

Alternative splicing results in multiple transcript variants encoding a single isoform

similar to several other members of the TRIM family

EphB1/2(Phospho Tyr594/604) Polyclonal Antibody, 20ul Antibody Humanization Disease-associated mutations tend to beEphrin receptors and their ligands, the ephrins, mediate numerous developmental processes, particularly in the nervous system. Based on their structures and sequence relationships, ephrins are divided into the ephrin A (EFNA) class, which are anchored to the membrane by a glycosylphosphatidylinositol linkage, and the ephrin B (EFNB) class, which are transmembrane proteins. The Eph family of receptors are divided into 2 groups based on the similarity