Stat3 Monoclonal Antibody, 50ul[BT-MCA1162] Vessels SESN1 encodes a member of

SESN1 encodes a member of the sestrin family

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Certain mutations in this gene resulting in a functionally inadequate enzyme are associated with a rare genetic disorder causing nonspherocytic hemolytic anemia

This gene is adjacent to another family member CLDN9 on chromosome 16

Stat3 Monoclonal Antibody, 50ul[BT-MCA1162] Vessels SESN1 encodes a member ofThe protein encoded by this gene is a member of the STAT protein family. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo or heterodimers that translocate to the cell nucleus where they act as transcription activators. This protein is activated through phosphorylation in response to various cytokines and growth factors including IFNs, EGF, IL5, IL6, HGF, LIF and