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ERR1 Polyclonal Antibody, 50ul Monoclonal Antibody Preparation The protein encoded by GAB2

SKU: 35888126837

4.4
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ERR1 Polyclonal Antibody, 50ul Monoclonal Antibody Preparation The protein encoded by GAB2The protein encoded by this gene is a nuclear receptor that is closely related to the estrogen receptor. This protein acts as a site specific transcription regulator and has been also shown to interact with estrogen and the transcripton factor TFIIB by direct protein protein contact. The binding and regulatory activities of this protein have been demonstrated in the regulation of a variety of genes including lactoferrin, osteopontin, medium chain acyl

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Description

The protein encoded by GAB2 is the principal activator of phosphatidylinositol-3 kinase in response to activation of the high affinity IgE receptor

The encoded protein has been shown to be able to bind to nucleic acid

The helix-loop-helix (HLH) proteins are a family of putative transcription factors

Phosphorylation on both Ser-362 and Ser-374 by MAPK1/2 and RSK1/2 leads to protein stabilization with phosphorylation on Ser-374 being the major site for protein stabilization on NGF stimulation

ERR1 Polyclonal Antibody, 50ul Monoclonal Antibody Preparation The protein encoded by GAB2The protein encoded by this gene is a nuclear receptor that is closely related to the estrogen receptor. This protein acts as a site specific transcription regulator and has been also shown to interact with estrogen and the transcripton factor TFIIB by direct protein protein contact. The binding and regulatory activities of this protein have been demonstrated in the regulation of a variety of genes including lactoferrin, osteopontin, medium chain acyl

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