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Rb(Phospho Ser249) Polyclonal Antibody, 50ul Immune Repertoire Sequencing Interacts with CUL7

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Rb(Phospho Ser249) Polyclonal Antibody, 50ul Immune Repertoire Sequencing Interacts with CUL7The protein encoded by this gene is a negative regulator of the cell cycle and was the first tumor suppressor gene found. The encoded protein also stabilizes constitutive heterochromatin to maintain the overall chromatin structure. The active, hypophosphorylated form of the protein binds transcription factor E2F1. Defects in this gene are a cause of childhood cancer retinoblastoma (RB), bladder cancer, and osteogenic sarcoma.

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Description

Interacts with CUL7

Required for poly-ubiquitination and proteasome-mediated degradation of CDKN1B during G1 phase of the cell cycle

These kinases are involved in the regulation of cell growth| differentiation and metabolism

B3GALT1 is a member of the beta-1

Rb(Phospho Ser249) Polyclonal Antibody, 50ul Immune Repertoire Sequencing Interacts with CUL7The protein encoded by this gene is a negative regulator of the cell cycle and was the first tumor suppressor gene found. The encoded protein also stabilizes constitutive heterochromatin to maintain the overall chromatin structure. The active, hypophosphorylated form of the protein binds transcription factor E2F1. Defects in this gene are a cause of childhood cancer retinoblastoma (RB), bladder cancer, and osteogenic sarcoma.

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