VEGF Receptor 2(Phospho-Tyr1212) Rabbit Polyclonal Antibody, 20ul sgRNA customized design Suppressor of cytokine signaling 2

Suppressor of cytokine signaling 2 encoded by SOCS2 interacts with the cytoplasmic domain of insulin-like growth factor-1 receptor (IGF1R) and is thought to be involved in the regulation of IGF1R mediated cell signaling

This gene encodes a high-affinity dickkopf homolog 1 (DKK1) transmembrane receptor that functionally cooperates with DKK1 to block wingless (WNT)/beta-catenin signaling

and neurological diseases

Ligand binding results in translocation of this protein to the nucleus

VEGF Receptor 2(Phospho-Tyr1212) Rabbit Polyclonal Antibody, 20ul sgRNA customized design Suppressor of cytokine signaling 2Vascular endothelial growth factor (VEGF) is a major growth factor for endothelial cells. This gene encodes one of the two receptors of the VEGF. This receptor known as kinase insert domain receptor is a type III receptor tyrosine kinase. It functions as the main mediator of VEGF induced endothelial proliferation survival migration tubular morphogenesis and sprouting. The signalling and trafficking of this receptor are regulated by multiple factors