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PKR Polyclonal Antibody, 100ul[BT-AP07244] Buffers & Solutions Another member of the CHP

SKU: 35733074224

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PKR Polyclonal Antibody, 100ul[BT-AP07244] Buffers & Solutions Another member of the CHPThe protein encoded by EIF2AK2 (eukaryotic translation initiation factor 2 alpha kinase 2) is a serine threonine protein kinase that is activated by autophosphorylation after binding to dsRNA. The activated form of the encoded protein can phosphorylate translation initiation factor EIF2S1, which in turn inhibits protein synthesis. This protein is also activated by manganese ions and heparin. Three transcript variants encoding two different isoforms

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Description

Another member of the CHP subfamily

as it contains characteristic adjacent cysteine residues

It catalyzes the synthesis of glutamine from glutamate and ammonia in an ATP-dependent reaction

RNA-binding abilities are down-regulated by tyrosine kinase PTK6

PKR Polyclonal Antibody, 100ul[BT-AP07244] Buffers & Solutions Another member of the CHPThe protein encoded by EIF2AK2 (eukaryotic translation initiation factor 2 alpha kinase 2) is a serine threonine protein kinase that is activated by autophosphorylation after binding to dsRNA. The activated form of the encoded protein can phosphorylate translation initiation factor EIF2S1, which in turn inhibits protein synthesis. This protein is also activated by manganese ions and heparin. Three transcript variants encoding two different isoforms

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