RUFY1 Polyclonal Antibody, 100ul Cell Culture Flasks The protease functions in the

The protease functions in the lysosome to cleave N-terminal tripeptides from substrates

is a 648 amino acid protein that localizes to both the nucleus and the cytoplasm and contains one protein kinase domain

in isoprenoid and sterol synthesis

enzyme regulation:Activated by phosphorylation on Thr-174 by STK11 in complex with STE20-related adapter-alpha (STRAD alpha) pseudo kinase and CAB39

RUFY1 Polyclonal Antibody, 100ul Cell Culture Flasks The protease functions in theRUFY1 (RUN and FYVE domain containing 1) encodes a protein that contains a RUN domain and a FYVE type zinc finger domain. The encoded protein binds to phosphatidylinositol 3 phosphate (PI3P) and plays a role in early endosomal trafficking, tethering and fusion through interactions with small GTPases including Rab4, Rab5 and Rab14. Alternatively spliced transcript variants encoding multiple isoforms have been observed for RUFY1.