c-Myc(Phospho Thr58) Polyclonal Antibody, 20ul Antibodies The protein acts as a

The protein acts as a DNA-binding transcriptional activator and regulates the heat-shock protein 70 (HSP70) promoter in a CCAAT-dependent manner

This gene is located in a gene cluster in a region on the long arm of chromosome 16 that is involved in loss of heterozygosity events in breast and prostate cancer

Two transcript variants encoding different isoforms (B and B') have been found for this gene

generating ATP and pyruvate

c-Myc(Phospho Thr58) Polyclonal Antibody, 20ul Antibodies The protein acts as aThe protein encoded by this gene is a multifunctional, nuclear phosphoprotein that plays a role in cell cycle progression, apoptosis and cellular transformation. It functions as a transcription factor that regulates transcription of specific target genes. Mutations, overexpression, rearrangement and translocation of this gene have been associated with a variety of hematopoietic tumors, leukemias and lymphomas, including Burkitt lymphoma. There is