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p53 Polyclonal Antibody, 50ul[BT-AP06814] Hepatocytes Most WFDC gene members are

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p53 Polyclonal Antibody, 50ul[BT-AP06814] Hepatocytes Most WFDC gene members areTP53 (tumor protein p53) encodes a tumor suppressor protein containing transcriptional activation, DNA binding, and oligomerization domains. The encoded protein responds to diverse cellular stresses to regulate expression of target genes, thereby inducing cell cycle arrest, apoptosis, senescence, DNA repair, or changes in metabolism. Mutations in TP53 are associated with a variety of human cancers, including hereditary cancers such as Li Fraumeni

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Description

Most WFDC gene members are localized to chromosome 20q12-q13 in two clusters: centromeric and telomeric

This gene is thought to be intronless

2001 [PubMed 11242035])

This gene is clustered with other MAGED genes on chromosome Xp11

p53 Polyclonal Antibody, 50ul[BT-AP06814] Hepatocytes Most WFDC gene members areTP53 (tumor protein p53) encodes a tumor suppressor protein containing transcriptional activation, DNA binding, and oligomerization domains. The encoded protein responds to diverse cellular stresses to regulate expression of target genes, thereby inducing cell cycle arrest, apoptosis, senescence, DNA repair, or changes in metabolism. Mutations in TP53 are associated with a variety of human cancers, including hereditary cancers such as Li Fraumeni

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